Ontology highlight
ABSTRACT:
SUBMITTER: Arbeev KG
PROVIDER: S-EPMC4725219 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Arbeev Konstantin G KG Cohen Alan A AA Arbeeva Liubov S LS Milot Emmanuel E Stallard Eric E Kulminski Alexander M AM Akushevich Igor I Ukraintseva Svetlana V SV Christensen Kaare K Yashin Anatoliy I AI
Frontiers in public health 20160125
While longitudinal changes in biomarker levels and their impact on health have been characterized for individual markers, little is known about how overall marker profiles may change during aging and affect mortality risk. We implemented the recently developed measure of physiological dysregulation based on the statistical distance of biomarker profiles in the framework of the stochastic process model of aging, using data on blood pressure, heart rate, cholesterol, glucose, hematocrit, body mass ...[more]