Ontology highlight
ABSTRACT:
SUBMITTER: Zhang Y
PROVIDER: S-EPMC4725338 | biostudies-literature | 2016 Jan
REPOSITORIES: biostudies-literature
Zhang Ying Y Fan Jieqing J Ho Joshua W K JW Hu Tommy T Kneeland Stephen C SC Fan Xueping X Xi Qiongchao Q Sellarole Michael A MA de Vries Wilhelmine N WN Lu Weining W Lachke Salil A SA Lang Richard A RA John Simon W M SW Maas Richard L RL
Development (Cambridge, England) 20151217 2
The developing lens is a powerful system for investigating the molecular basis of inductive tissue interactions and for studying cataract, the leading cause of blindness. The formation of tightly controlled cell-cell adhesions and cell-matrix junctions between lens epithelial (LE) cells, between lens fiber (LF) cells, and between these two cell populations enables the vertebrate lens to adopt a highly ordered structure and acquire optical transparency. Adhesion molecules are thought to maintain ...[more]