Design and Fabrication of 3D printed Scaffolds with a Mechanical Strength Comparable to Cortical Bone to Repair Large Bone Defects.
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ABSTRACT:
SUBMITTER: Roohani-Esfahani SI
PROVIDER: S-EPMC4726111 | biostudies-literature | 2016 Jan
REPOSITORIES: biostudies-literature
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Design and Fabrication of 3D printed Scaffolds with a Mechanical Strength Comparable to Cortical Bone to Repair Large Bone Defects.
Roohani-Esfahani Seyed-Iman SI Newman Peter P Zreiqat Hala H
Scientific reports 20160119
A challenge in regenerating large bone defects under load is to create scaffolds with large and interconnected pores while providing a compressive strength comparable to cortical bone (100-150 MPa). Here we design a novel hexagonal architecture for a glass-ceramic scaffold to fabricate an anisotropic, highly porous three dimensional scaffolds with a compressive strength of 110 MPa. Scaffolds with hexagonal design demonstrated a high fatigue resistance (1,000,000 cycles at 1-10 MPa compressive cy ...[more]
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