Ontology highlight
ABSTRACT:
SUBMITTER: Song NJ
PROVIDER: S-EPMC4726366 | biostudies-literature | 2016 Jan
REPOSITORIES: biostudies-literature
Song No-Joon NJ Yun Ui Jeong UJ Yang Sunghee S Wu Chunyan C Seo Cho-Rong CR Gwon A-Ryeong AR Baik Sang-Ha SH Choi Yuri Y Choi Bo Youn BY Bahn Gahee G Kim Suji S Kwon So-Mi SM Park Jin Su JS Baek Seung Hyun SH Park Tae Joo TJ Yoon Keejung K Kim Byung-Joon BJ Mattson Mark P MP Lee Sung-Joon SJ Jo Dong-Gyu DG Park Kye Won KW
Scientific reports 20160120
Notch signaling pathways modulate various cellular processes, including cell proliferation, differentiation, adhesion, and communication. Recent studies have demonstrated that Notch1 signaling also regulates hepatic glucose production and lipid synthesis. However, the effect of Notch1 signaling on hepatic lipid oxidation has not yet been directly investigated. To define the function of Notch1 signaling in hepatic lipid metabolism, wild type mice and Notch1 deficient antisense transgenic (NAS) mi ...[more]