Ontology highlight
ABSTRACT:
SUBMITTER: Itano MS
PROVIDER: S-EPMC4729623 | biostudies-literature | 2016 Feb
REPOSITORIES: biostudies-literature
Traffic (Copenhagen, Denmark) 20151214 2
Human immunodeficiency virus (HIV)-1 infection and the associated disease AIDS are a major cause of human death worldwide with no vaccine or cure available. The trafficking of HIV-1 RNAs from sites of synthesis in the nucleus, through the cytoplasm, to sites of assembly at the plasma membrane are critical steps in HIV-1 viral replication, but are not well characterized. Here we present a broadly accessible microscopy method that captures multiple focal planes simultaneously, which allows us to i ...[more]