Ontology highlight
ABSTRACT:
SUBMITTER: Sedzinski J
PROVIDER: S-EPMC4735878 | biostudies-literature | 2016 Jan
REPOSITORIES: biostudies-literature
Sedzinski Jakub J Hannezo Edouard E Tu Fan F Biro Maté M Wallingford John B JB
Developmental cell 20160101 1
Epithelial sheets are crucial components of all metazoan animals, enclosing organs and protecting the animal from its environment. Epithelial homeostasis poses unique challenges, as addition of new cells and loss of old cells must be achieved without disrupting the fluid-tight barrier and apicobasal polarity of the epithelium. Several studies have identified cell biological mechanisms underlying extrusion of cells from epithelia, but far less is known of the converse mechanism by which new cells ...[more]