Ontology highlight
ABSTRACT:
SUBMITTER: Ternette N
PROVIDER: S-EPMC4737398 | biostudies-literature | 2016 Jan
REPOSITORIES: biostudies-literature
Ternette Nicola N Yang Hongbing H Partridge Thomas T Llano Anuska A Cedeño Samandhy S Fischer Roman R Charles Philip D PD Dudek Nadine L NL Mothe Beatriz B Crespo Manuel M Fischer William M WM Korber Bette T M BT Nielsen Morten M Borrow Persephone P Purcell Anthony W AW Brander Christian C Dorrell Lucy L Kessler Benedikt M BM Hanke Tomáš T
European journal of immunology 20151104 1
Recognition and eradication of infected cells by cytotoxic T lymphocytes is a key defense mechanism against intracellular pathogens. High-throughput definition of HLA class I-associated immunopeptidomes by mass spectrometry is an increasingly important analytical tool to advance our understanding of the induction of T-cell responses against pathogens such as HIV-1. We utilized a liquid chromatography tandem mass spectrometry workflow including de novo-assisted database searching to define the HL ...[more]