Ontology highlight
ABSTRACT:
SUBMITTER: Imamura M
PROVIDER: S-EPMC4738362 | biostudies-literature | 2016 Jan
REPOSITORIES: biostudies-literature
Nature communications 20160128
Genome-wide association studies (GWAS) have identified more than 80 susceptibility loci for type 2 diabetes (T2D), but most of its heritability still remains to be elucidated. In this study, we conducted a meta-analysis of GWAS for T2D in the Japanese population. Combined data from discovery and subsequent validation analyses (23,399 T2D cases and 31,722 controls) identify 7 new loci with genome-wide significance (P<5 × 10(-8)), rs1116357 near CCDC85A, rs147538848 in FAM60A, rs1575972 near DMRTA ...[more]