Ontology highlight
ABSTRACT:
SUBMITTER: Magbanua MJ
PROVIDER: S-EPMC4741563 | biostudies-literature | 2015 Oct
REPOSITORIES: biostudies-literature
Magbanua Mark Jesus M MJ Das Rishi R Polavarapu Prithi P Park John W JW
Oncotarget 20151001 31
Micrometastatic cells in the bone marrow, now usually referred to as "disseminated tumor cells (DTCs)", can be detected in early stage cancer patients. It has been hypothesized that DTCs represent key intermediates in the metastatic process as possible precursors of bone and visceral metastases, and are indicators of metastatic potential. Indeed, multiple clinical studies have unequivocally demonstrated the prognostic value of these cells in breast and other cancers, as DTCs have been associated ...[more]