Biophysical EPR Studies Applied to Membrane Proteins.

ABSTRACT: Membrane proteins are very important in controlling bioenergetics, functional activity, and initializing signal pathways in a wide variety of complicated biological systems. They also represent approximately 50% of the potential drug targets. EPR spectroscopy is a very popular and powerful biophysical tool that is used to study the structural and dynamic properties of membrane proteins. In this article, a basic overview of the most commonly used EPR techniques and examples of recent applications to answer pertinent structural and dynamic related questions on membrane protein systems will be presented.

SUBMITTER: Sahu ID 

PROVIDER: S-EPMC4742357 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature