Unknown

Dataset Information

0

Dependence of Protein Structure on Environment: FOD Model Applied to Membrane Proteins.


ABSTRACT: The natural environment of proteins is the polar aquatic environment and the hydrophobic (amphipathic) environment of the membrane. The fuzzy oil drop model (FOD) used to characterize water-soluble proteins, as well as its modified version FOD-M, enables a mathematical description of the presence and influence of diverse environments on protein structure. The present work characterized the structures of membrane proteins, including those that act as channels, and a water-soluble protein for contrast. The purpose of the analysis was to verify the possibility that an external force field can be used in the simulation of the protein-folding process, taking into account the diverse nature of the environment that guarantees a structure showing biological activity.

SUBMITTER: Roterman I 

PROVIDER: S-EPMC8778870 | biostudies-literature |

REPOSITORIES: biostudies-literature

Similar Datasets

| S-EPMC2374085 | biostudies-literature
| S-EPMC8508659 | biostudies-literature
| S-EPMC4742357 | biostudies-literature
| S-EPMC3610044 | biostudies-literature
| S-EPMC6213535 | biostudies-literature
| S-EPMC9322369 | biostudies-literature
| S-EPMC8580007 | biostudies-literature
| S-EPMC3145270 | biostudies-literature
| S-EPMC8654985 | biostudies-literature
| S-EPMC5172438 | biostudies-literature