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Neural Mechanisms of Post-error Adjustments of Decision Policy in Parietal Cortex.

ABSTRACT: Humans often slow down after mistakes (post-error slowing [PES]), but the neural mechanism and adaptive role of PES remain controversial. We studied changes in the neural mechanisms of decision making after errors in humans and monkeys that performed a motion direction discrimination task. We found that PES is mediated by two factors: a reduction in sensitivity to sensory information and an increase in the decision bound. Both effects are implemented through dynamic changes in the decision-making process. Neuronal responses in the monkey lateral intraparietal area revealed that bound changes are implemented by decreasing an evidence-independent urgency signal. They also revealed a reduction in the rate of evidence accumulation, reflecting reduced sensitivity. These changes in the bound and sensitivity provide a quantitative account of choices and response times. We suggest that PES reflects an adaptive increase of decision bound in anticipation of maladaptive reductions in sensitivity to incoming evidence.

SUBMITTER: Purcell BA

PROVIDER: S-EPMC4742416 | biostudies-literature | 2016 Feb

REPOSITORIES: biostudies-literature

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Neural Mechanisms of Post-error Adjustments of Decision Policy in Parietal Cortex.

Purcell Braden A BA Kiani Roozbeh R

Neuron 20160121 3

Humans often slow down after mistakes (post-error slowing [PES]), but the neural mechanism and adaptive role of PES remain controversial. We studied changes in the neural mechanisms of decision making after errors in humans and monkeys that performed a motion direction discrimination task. We found that PES is mediated by two factors: a reduction in sensitivity to sensory information and an increase in the decision bound. Both effects are implemented through dynamic changes in the decision-makin ...[more]

PMID: 26804992

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