Ontology highlight
ABSTRACT:
SUBMITTER: Draisma HHM
PROVIDER: S-EPMC4745136 | biostudies-literature | 2015 Jun
REPOSITORIES: biostudies-literature
Nature communications 20150612
Metabolites are small molecules involved in cellular metabolism, which can be detected in biological samples using metabolomic techniques. Here we present the results of genome-wide association and meta-analyses for variation in the blood serum levels of 129 metabolites as measured by the Biocrates metabolomic platform. In a discovery sample of 7,478 individuals of European descent, we find 4,068 genome- and metabolome-wide significant (Z-test, P < 1.09 × 10(-9)) associations between single-nucl ...[more]