Ontology highlight
ABSTRACT:
SUBMITTER: Wang K
PROVIDER: S-EPMC4746220 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Wang Karin K Seo Bo Ri BR Fischbach Claudia C Gourdon Delphine D
Cellular and molecular bioengineering 20150815
Fibronectin (Fn) is an essential extracellular matrix (ECM) glycoprotein involved in both physiological and pathological processes. The structure-function relationship of Fn has been and is still being studied, as changes in its molecular structure are integral in regulating (or dysregulating) its biological activities <i>via</i> its cell, matrix component, and growth factor binding sites. Fn comprises three types of repeating modules; among them, FnIII modules are mechanically unstable domains ...[more]