Ontology highlight
ABSTRACT:
SUBMITTER: Zhang Z
PROVIDER: S-EPMC4746620 | biostudies-literature | 2016 Feb
REPOSITORIES: biostudies-literature
Zhang Zhiguo Z Li Bo B Meng Xiangjian X Yao Shuangshuang S Jin Lina L Yang Jian J Wang Jiqiu J Zhang Huizhi H Zhang Zhijian Z Cai Dongsheng D Zhang Yifei Y Ning Guang G
Scientific reports 20160209
The histological spectrum of nonalcoholic fatty liver diseases (NAFLD) ranges from hepatic steatosis to steatohepatitis and fibrosis. Berberine (BBR) is known for its therapeutic effect on obesity, hyperglycaemia and dyslipidaemia; however, its effect on NAFLD has yet to be thoroughly explored. Db/db mice and methionine-choline-deficient diet-fed mice were administered BBR via gavage. We found that BBR-treated mice were more resistant to steatosis in the liver than vehicle-treated mice and that ...[more]