Dataset Information

Image Quality Analysis of Eyes Undergoing LASER Refractive Surgery.

ABSTRACT: Laser refractive surgery for myopia increases the eye's higher-order wavefront aberrations (HOA's). However, little is known about the impact of such optical degradation on post-operative image quality (IQ) of these eyes. This study determined the relation between HOA's and IQ parameters (peak IQ, dioptric focus that maximized IQ and depth of focus) derived from psychophysical (logMAR acuity) and computational (logVSOTF) through-focus curves in 45 subjects (18 to 31 yrs) before and 1-month after refractive surgery and in 40 age-matched emmetropic controls. Computationally derived peak IQ and its best focus were negatively correlated with the RMS deviation of all HOA's (HORMS) (r?-0.5; p<0.001 for all). Computational depth of focus was positively correlated with HORMS (r?0.55; p<0.001 for all) and negatively correlated with peak IQ (r?-0.8; p<0.001 for all). All IQ parameters related to logMAR acuity were poorly correlated with HORMS (r?|0.16|; p>0.16 for all). Increase in HOA's after refractive surgery is therefore associated with a decline in peak IQ and a persistence of this sub-standard IQ over a larger dioptric range, vis-à-vis, before surgery and in age-matched controls. This optical deterioration however does not appear to significantly alter psychophysical IQ, suggesting minimal impact of refractive surgery on the subject's ability to resolve spatial details and their tolerance to blur.

SUBMITTER: Sarkar S

PROVIDER: S-EPMC4747534 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature

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Image Quality Analysis of Eyes Undergoing LASER Refractive Surgery.

Sarkar Samrat S Vaddavalli Pravin Krishna PK Bharadwaj Shrikant R SR

PloS one 20160209 2

Laser refractive surgery for myopia increases the eye's higher-order wavefront aberrations (HOA's). However, little is known about the impact of such optical degradation on post-operative image quality (IQ) of these eyes. This study determined the relation between HOA's and IQ parameters (peak IQ, dioptric focus that maximized IQ and depth of focus) derived from psychophysical (logMAR acuity) and computational (logVSOTF) through-focus curves in 45 subjects (18 to 31 yrs) before and 1-month after ...[more]

PMID: 26859302

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Project description:Purpose:To evaluate the effect of laser refractive surgery on sensory eye dominance of anisometropia. Methods:A total of 156 subjects with nonanisometropic myopia and 70 subjects with anisometropic myopia were enrolled in the first part of the study. The dichoptic motion coherence threshold technique was applied to collect the normal dataset and distribution of sensory eye dominance. The second part of the study included 40 subjects with nonanisometropic myopia and 40 subjects with anisometropic myopia who received the femtosecond laser-assisted in situ keratomileusis (Fs-LASIK). A comprehensive ophthalmologic evaluation was performed with particular attention to sensory eye dominance preoperatively and one-week and one-month postoperatively. The ocular dominance index (ODI) was applied to evaluate the subject's overall degree of sensory ocular dominance. Visual acuity, sighting eye dominance, and stereo acuity were also accessed. Results:In experiment one, the mean ODI in the nonanisometropic group and the anisometropic group was 1.48?±?0.63 and 1.95?±?1.07, respectively. The ODI values of the anisometropic group were significantly higher than those of the nonanisometropic group (Mann-Whitney U test, P < 0.001). The demographics information and the distribution of ODI values in both groups are summarized in tables and figures. In experiment two, all LASIK procedures were uneventful and no postoperative complications were observed during the postoperative follow-up. Preoperatively, the ODI values of the anisometropic LASIK group were significantly higher than those of the nonanisometropic LASIK group, which was consistent with the results of part 1. However, one week after operation, the mean ODI values of the anisometropic LASIK group had significantly decreased from 1.89?±?1.09 to 1.39?±?0.44. And, the mean ODI values slightly increased to 1.65?±?0.61 one-month postoperatively. In the nonanisometropic LASIK group, there were no statistically significant differences of ODI changes among preoperative, post-one-week and post-one-month visits. The demographics information and the changes of ODI of both LASIK groups are summarized in tables and figures. Conclusion:Stronger sensory eye dominance is seen in the subjects with anisometropic myopia compared to subjects with nonanisometropic myopia. The strong sensory dominance of anisometropia becomes more balanced at one week of postoperation but returns to the preoperative level after one month. Laser refractive surgery had a short-term modulation of sensory eye dominance.

Project description:PurposeCurrently, there are no UK optometric guidelines regarding the pre and postoperative refractive management of patients undergoing cataract surgery. This study used a Delphi method to gain consensus on best practice.MethodsEighteen recommendations targeted areas of concern/variability in advice that were highlighted in an earlier focus group study of refractive management for patients who had received cataract surgery. These covered three topics: preoperative target refraction discussions, postoperative refractive management and driving advice postoperatively. The recommendations were then developed using evidence from optometry and ophthalmology clinical expertise and the research literature. Eighteen recommendations underwent a process of agreement and modification using a Delphi study consisting of a panel of 22 highly experienced optometrists (N = 11, 25 years mean clinical experience) and ophthalmologists (N = 11, 17 years mean clinical experience) who rated and commented upon the importance and feasibility of each recommendation. The responses were considered by the research team and the recommendations modified and/or removed prior to a second Delphi round of responses to a modified series of recommendations. Consensus of opinion was defined as greater than 80% of panellists 'agreed' or 'strongly agreed' on the recommendation for both importance and feasibility.ResultsFourteen of the 18 recommendations reached consensus in the first round. A second round of the Delphi method saw 17 modified recommendations scored and commented upon by 20 clinicians. Fifteen recommendations reached consensus after two rounds of the Delphi method.ConclusionsRecommendations to guide the pre and postoperative refractive management of patients undergoing cataract surgery were agreed between highly experienced optometrists and ophthalmologists using a 2-round Delphi method. Patients would benefit from consistent target refraction discussions, postoperative refractive management and driving advice, and recommendations were of particular benefit to less experienced optometrists.

Dataset Information

Image Quality Analysis of Eyes Undergoing LASER Refractive Surgery.

Publications

Image Quality Analysis of Eyes Undergoing LASER Refractive Surgery.

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