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Genetically anchored fluorescent probes for subcellular specific imaging of hydrogen sulfide.

ABSTRACT: Imaging hydrogen sulfide (H2S) at the subcellular resolution will greatly improve the understanding of functions of this signaling molecule. Taking advantage of the protein labeling technologies, we report a general strategy for the development of organelle specific H2S probes, which enables sub-cellular H2S imaging essentially in any organelles of interest.

SUBMITTER: Chen J

PROVIDER: S-EPMC4747831 | biostudies-literature | 2016 Feb

REPOSITORIES: biostudies-literature

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Genetically anchored fluorescent probes for subcellular specific imaging of hydrogen sulfide.

Chen Jianwei J Zhao Mingkun M Jiang Xiqian X Sizovs Antons A Wang Meng C MC Provost Christopher R CR Huang Jia J Wang Jin J

The Analyst 20160201 4

Imaging hydrogen sulfide (H2S) at the subcellular resolution will greatly improve the understanding of functions of this signaling molecule. Taking advantage of the protein labeling technologies, we report a general strategy for the development of organelle specific H2S probes, which enables sub-cellular H2S imaging essentially in any organelles of interest. ...[more]

PMID: 26806071

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