Ontology highlight
ABSTRACT:
SUBMITTER: Furuyama W
PROVIDER: S-EPMC4748290 | biostudies-literature | 2016 Feb
REPOSITORIES: biostudies-literature
Furuyama Wakako W Marzi Andrea A Nanbo Asuka A Haddock Elaine E Maruyama Junki J Miyamoto Hiroko H Igarashi Manabu M Yoshida Reiko R Noyori Osamu O Feldmann Heinz H Takada Ayato A
Scientific reports 20160210
During the latest outbreak of Ebola virus disease in West Africa, monoclonal antibody therapy (e.g., ZMapp) was utilized to treat patients. However, due to the antigenic differences among the five ebolavirus species, the current therapeutic monoclonal antibodies are only effective against viruses of the species Zaire ebolavirus. Although this particular species has indeed caused the majority of human infections in Central and, recently, West Africa, other ebolavirus species (e.g., Sudan ebolavir ...[more]