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Interfacial nano-biosensing in microfluidic droplets for high-sensitivity detection of low-solubility molecules.


ABSTRACT: Taking advantage of the properties of the high surface-area-to-volume ratio of microfluidic droplets, we developed an innovative interfacial nanosensing strategy based on aptamer-functionalized graphene oxide nanosensors in microfluidic droplets for the high-sensitivity one-step detection of 17?-estradiol and other low-solubility molecules, with the detection sensitivity improved by about 3 orders of magnitude compared to conventional systems.

SUBMITTER: Dou M 

PROVIDER: S-EPMC4760840 | biostudies-literature | 2016 Feb

REPOSITORIES: biostudies-literature

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Interfacial nano-biosensing in microfluidic droplets for high-sensitivity detection of low-solubility molecules.

Dou Maowei M   García José Mireles JM   Zhan Sihui S   Li XiuJun X  

Chemical communications (Cambridge, England) 20160113 17


Taking advantage of the properties of the high surface-area-to-volume ratio of microfluidic droplets, we developed an innovative interfacial nanosensing strategy based on aptamer-functionalized graphene oxide nanosensors in microfluidic droplets for the high-sensitivity one-step detection of 17β-estradiol and other low-solubility molecules, with the detection sensitivity improved by about 3 orders of magnitude compared to conventional systems. ...[more]

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