Ontology highlight
ABSTRACT:
SUBMITTER: Padilla-Coreano N
PROVIDER: S-EPMC4760847 | biostudies-literature | 2016 Feb
REPOSITORIES: biostudies-literature
Padilla-Coreano Nancy N Bolkan Scott S SS Pierce Georgia M GM Blackman Dakota R DR Hardin William D WD Garcia-Garcia Alvaro L AL Spellman Timothy J TJ Gordon Joshua A JA
Neuron 20160204 4
The ventral hippocampus (vHPC), medial prefrontal cortex (mPFC), and basolateral amygdala (BLA) are each required for the expression of anxiety-like behavior. Yet the role of each individual element of the circuit is unclear. The projection from the vHPC to the mPFC has been implicated in anxiety-related neural synchrony and spatial representations of aversion. The role of this projection was examined using multi-site neural recordings combined with optogenetic terminal inhibition. Inhibition of ...[more]