Ontology highlight
ABSTRACT:
SUBMITTER: Seftel MD
PROVIDER: S-EPMC4764423 | biostudies-literature | 2016 Mar
REPOSITORIES: biostudies-literature
Seftel Matthew D MD Neuberg Donna D Zhang Mei-Jie MJ Wang Hai-Lin HL Ballen Karen Kuhn KK Bergeron Julie J Couban Stephen S Freytes César O CO Hamadani Mehdi M Kharfan-Dabaja Mohamed A MA Lazarus Hillard M HM Nishihori Taiga T Paulson Kristjan K Saber Wael W Sallan Stephen E SE Soiffer Robert R Tallman Martin S MS Woolfrey Ann E AE DeAngelo Daniel J DJ Weisdorf Daniel J DJ
American journal of hematology 20160301 3
For adults with Philadelphia chromosome-negative (Ph-) acute lymphoblastic leukemia (ALL) in first complete remission (CR1), allogeneic hematopoietic cell transplantation (HCT) is an established curative strategy. However, pediatric-inspired chemotherapy may also offer durable leukemia-free survival in the absence of HCT. We compared 422 HCT recipients aged 18-50 years with Ph-ALL in CR1 reported to the CIBMTR with an age-matched concurrent cohort of 108 Ph- ALL CR1 patients who received a Dana- ...[more]