Ontology highlight
ABSTRACT:
SUBMITTER: Thomas X
PROVIDER: S-EPMC6171979 | biostudies-literature | 2016 Sep
REPOSITORIES: biostudies-literature
International journal of hematologic oncology 20160923 2
The outcome of adult patients with Philadelphia chromosome-positive (Ph<sup>+</sup>) acute lymphoblastic leukemia (ALL) has improved substantially with the introduction of tyrosine kinase inhibitors (TKIs). TKIs are now integral components of therapy for Ph<sup>+</sup> ALL. The current consensus is that they improve patient outcomes compared with historical control patients treated with chemotherapy alone, and increase the number of patients able to receive stem cell transplant. New challenges h ...[more]