Ontology highlight
ABSTRACT:
SUBMITTER: Jin C
PROVIDER: S-EPMC4764980 | biostudies-literature | 2016 Feb
REPOSITORIES: biostudies-literature
Jin Chengzhi C Liu Jiangping J Chen Yu Y Guan Ruilin R Ouyang Cheng C Zhu Yanjiao Y Ji Liangnian L Chao Hui H
Scientific reports 20160224
Mitophagy, which is a special autophagy that removes damaging mitochondria to maintain sufficient healthy mitochondria, provides an alternative path for addressing dysfunctional mitochondria and avoiding cellular death. In the present study, by coupling the triphenylamine group with 2-phenylimidazo[4,5-f][1,10]phenanthroline derivatives, we synthesized five Ir(III) complexes with an AIE property that are expected to fulfill requirements for real-time monitoring of mitophagy. Ir1-Ir5 were exploit ...[more]