Ontology highlight
ABSTRACT:
SUBMITTER: Raftopoulos H
PROVIDER: S-EPMC4766217 | biostudies-literature | 2016 Apr
REPOSITORIES: biostudies-literature
Raftopoulos Haralambos H Laadem Abderrahmane A Hesketh Paul J PJ Goldschmidt Jerome J Gabrail Nashat N Osborne Cynthia C Ali Muhammad M Sherman Matthew L ML Wang Ding D Glaspy John A JA Puccio-Pick Marie M Zou Jun J Crawford Jeffrey J
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20150914 4
<h4>Purpose</h4>Sotatercept may represent a novel approach to the treatment of chemotherapy-induced anemia (CIA). We report the results from two phase 2 randomized studies examining the use of sotatercept for the treatment of CIA in patients with metastatic cancer.<h4>Methods</h4>In study A011-08, patients with metastatic breast cancer were randomized to 2:2:2:1 to receive sotatercept 0.1, 0.3, or 0.5 mg/kg, or placebo, respectively, every 28 days. In study ACE-011-NSCL-001, patients with solid ...[more]