High frame-rate resolution of cell division during Candida albicans filamentation.
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ABSTRACT:
SUBMITTER: Thomson DD
PROVIDER: S-EPMC4767323 | biostudies-literature | 2016 Mar
REPOSITORIES: biostudies-literature
Publications
High frame-rate resolution of cell division during Candida albicans filamentation.
Thomson Darren D DD Berman Judith J Brand Alexandra C AC
Fungal genetics and biology : FG & B 20160204
The commensal yeast, Candida albicans, is an opportunistic pathogen in humans and forms filaments called hyphae and pseudohyphae, in which cell division requires precise temporal and spatial control to produce mononuclear cell compartments. High-frame-rate live-cell imaging (1 frame/min) revealed that nuclear division did not occur across the septal plane. We detected the presence of nucleolar fragments that may be extrachromosomal molecules carrying the ribosomal RNA genes. Cells occasionally m ...[more]
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