Ontology highlight
ABSTRACT:
SUBMITTER: Dite GS
PROVIDER: S-EPMC4767544 | biostudies-literature | 2016 Feb
REPOSITORIES: biostudies-literature
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20151216 2
<h4>Background</h4>The extent to which clinical breast cancer risk prediction models can be improved by including information on known susceptibility SNPs is not known.<h4>Methods</h4>Using 750 cases and 405 controls from the population-based Australian Breast Cancer Family Registry who were younger than 50 years at diagnosis and recruitment, respectively, Caucasian and not BRCA1 or BRCA2 mutation carriers, we derived absolute 5-year risks of breast cancer using the BOADICEA, BRCAPRO, BCRAT, and ...[more]