Chemotherapy-Induced Intestinal Mucosal Barrier Damage: a Cause of Falsely Elevated Serum 1,3-Beta-d-Glucan Levels?
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SUBMITTER: Prattes J
PROVIDER: S-EPMC4767967 | biostudies-literature | 2016 Mar
REPOSITORIES: biostudies-literature
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Chemotherapy-Induced Intestinal Mucosal Barrier Damage: a Cause of Falsely Elevated Serum 1,3-Beta-d-Glucan Levels?
Prattes Juergen J Raggam Reinhard B RB Vanstraelen Kim K Rabensteiner Jasmin J Hoegenauer Christoph C Krause Robert R Prüller Florian F Wölfler Albert A Spriet Isabel I Hoenigl Martin M
Journal of clinical microbiology 20151230 3
Blood citrulline and intestinal fatty acid binding protein were determined as biomarkers for intestinal mucositis. Biomarker levels were correlated with corresponding serum 1,3-beta-D-glucan levels in 56 samples obtained from 33 cases with underlying hematological malignancies receiving induction chemotherapy. No correlation between biomarkers of intestinal mucositis and BDG levels was observed. (This study has been registered at ClinicalTrials.gov under registration no. NCT01576653.). ...[more]
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