Ontology highlight
ABSTRACT:
SUBMITTER: Ding L
PROVIDER: S-EPMC4770186 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Ding Lan L Styblo Miroslav M Drobná Zuzana Z Hegde Ashok N AN
Frontiers in psychiatry 20160229
The Regulator of G protein signaling 4 (RGS4) gene is a candidate susceptibility gene for schizophrenia (SCZ). Previous studies showed that the mRNA level of the longest splice variant RGS4-1 was decreased in the dorsolateral prefrontal cortex (DLPFC) of SCZ patients compared with healthy controls. In this pilot study, we examined the possible mechanisms of RGS4-1 mRNA reduction in SCZ. We genotyped SNP1 (rs10917670), rs2661347, SNP4 (rs951436), SNP7 (rs951439), SNP18 (rs2661319), and rs10799897 ...[more]