Ontology highlight
ABSTRACT:
SUBMITTER: Wang H
PROVIDER: S-EPMC4770280 | biostudies-literature | 2016 Feb
REPOSITORIES: biostudies-literature
Wang Haolu H Liang Xiaowen X Xu Zhi Ping ZP Crawford Darrell H G DH Liu Xin X Roberts Michael S MS
Scientific reports 20160229
Although mesenchymal stem cells (MSCs) present a promising tool in cell therapy for the treatment of various diseases, the in vivo distribution of administered MSCs has still been poorly understood, which hampers the precise prediction and evaluation of their therapeutic efficacy. Here, we developed the first model to characterize the physiological kinetics of administered MSCs based on direct visualization of cell spatiotemporal disposition by intravital microscopy and assessment of cell quanti ...[more]