Ontology highlight
ABSTRACT:
SUBMITTER: Maeda K
PROVIDER: S-EPMC4770287 | biostudies-literature | 2016 Feb
REPOSITORIES: biostudies-literature
Maeda Keiko K Enomoto Atsushi A Hara Akitoshi A Asai Naoya N Kobayashi Takeshi T Horinouchi Asuka A Maruyama Shoichi S Ishikawa Yuichi Y Nishiyama Takahiro T Kiyoi Hitoshi H Kato Takuya T Ando Kenju K Weng Liang L Mii Shinji S Asai Masato M Mizutani Yasuyuki Y Watanabe Osamu O Hirooka Yoshiki Y Goto Hidemi H Takahashi Masahide M
Scientific reports 20160229
Bone marrow-derived mesenchymal stromal cells (BM-MSCs) in culture are derived from BM stromal cells or skeletal stem cells. Whereas MSCs have been exploited in clinical medicine, the identification of MSC-specific markers has been limited. Here, we report that a cell surface and secreted protein, Meflin, is expressed in cultured MSCs, fibroblasts and pericytes, but not other types of cells including epithelial, endothelial and smooth muscle cells. In vivo, Meflin is expressed by immature osteob ...[more]