Ontology highlight
ABSTRACT:
SUBMITTER: Wang S
PROVIDER: S-EPMC4367509 | biostudies-other | 2015 Apr
REPOSITORIES: biostudies-other
Wang Shuyun S Mundada Lakshmi L Johnson Sean S Wong Joshua J Witt Russell R Ohye Richard G RG Si Ming-Sing MS
Stem cells translational medicine 20150223 4
Resident mesenchymal stromal cells (MSCs) are involved in angiogenesis during thymus regeneration. We have previously shown that MSCs can be isolated from enzymatically digested human neonatal and infant thymus tissue that is normally discarded during pediatric cardiac surgical procedures. In this paper, we demonstrate that thymus MSCs can also be isolated by explant culture of discarded thymus tissue and that these cells share many of the characteristics of bone marrow MSCs. Human neonatal thym ...[more]