Ontology highlight
ABSTRACT:
SUBMITTER: Xu D
PROVIDER: S-EPMC4775016 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Xu Dengfeng D Yi Hong H Yu Shizhi S Li Xiaosong X Qiao Yanbin Y Deng Weiwei W
PloS one 20160302 3
<h4>Purpose</h4>To investigate the association of C5 SNPs with proliferative diabetic retinopathy (PDR) of type 2 diabetes (T2D).<h4>Methods</h4>A total of four C5 SNPs including rs2269067, rs7040033, rs1017119 and rs7027797 were genotyped in 400 PDR patients with T2D (cases) and 600 non- proliferative diabetic retinopathy PDR (NPDR) with T2D patients (controls) by using PCR-RFLP method. mRNA expression was examined by real-time PCR. Cytokine production was detected by ELISA.<h4>Results</h4>The ...[more]