Ontology highlight
ABSTRACT:
SUBMITTER: Sandmann R
PROVIDER: S-EPMC4776100 | biostudies-literature | 2016 Mar
REPOSITORIES: biostudies-literature
Sandmann Rabea R Köster Sarah S
Scientific reports 20160303
Blood platelets are instrumental in blood clotting and are thus heavily involved in early wound closure. After adhering to a substrate they spread by forming protrusions like lamellipodia and filopodia. However, the interaction of these protrusions with the physical environment of platelets while spreading is not fully understood. Here we dynamically image platelets during this spreading process and compare their behavior on smooth and on structured substrates. In particular we analyze the tempo ...[more]