Ontology highlight
ABSTRACT:
SUBMITTER: Liu F
PROVIDER: S-EPMC4777318 | biostudies-literature | 2016 Feb
REPOSITORIES: biostudies-literature
Liu Fei F Koval Michael M Ranganathan Shoba S Fanayan Susan S Hancock William S WS Lundberg Emma K EK Beavis Ronald C RC Lane Lydie L Duek Paula P McQuade Leon L Kelleher Neil L NL Baker Mark S MS
Journal of proteome research 20160112 2
Claudins are the major transmembrane protein components of tight junctions in human endothelia and epithelia. Tissue-specific expression of claudin members suggests that this protein family is not only essential for sustaining the role of tight junctions in cell permeability control but also vital in organizing cell contact signaling by protein-protein interactions. How this protein family is collectively processed and regulated is key to understanding the role of junctional proteins in preservi ...[more]