Ontology highlight
ABSTRACT:
SUBMITTER: Silvennoinen R
PROVIDER: S-EPMC4777887 | biostudies-literature | 2016 Mar
REPOSITORIES: biostudies-literature
Silvennoinen R R Anttila P P Säily M M Lundan T T Heiskanen J J Siitonen T M TM Kakko S S Putkonen M M Ollikainen H H Terävä V V Kutila A A Launonen K K Räsänen A A Sikiö A A Suominen M M Bazia P P Kananen K K Selander T T Kuittinen T T Remes K K Jantunen E E
Bone marrow transplantation 20151005 3
The most common means of mobilizing autologous stem cells is G-CSF alone or combined with cyclophosphamide (CY) to obtain sufficient CD34+ cells for one to two transplants. There are few prospective, randomized studies investigating mobilization regimens in multiple myeloma (MM), especially after lenalidomide-based induction. We designed this prospective, randomized study to compare low-dose CY 2 g/m2 +G-CSF (arm A) and G-CSF alone (arm B) after lenalidomide-based up-front induction in MM. Of th ...[more]