Ontology highlight
ABSTRACT:
SUBMITTER: Sadowski JH
PROVIDER: S-EPMC4785795 | biostudies-literature | 2016 Mar
REPOSITORIES: biostudies-literature
Cell reports 20160218 8
Place cell firing patterns reactivated during hippocampal sharp-wave ripples (SWRs) in rest or sleep are thought to induce synaptic plasticity and thereby promote the consolidation of recently encoded information. However, the capacity of reactivated spike trains to induce plasticity has not been directly tested. Here, we show that reactivated place cell firing patterns simultaneously recorded from CA3 and CA1 of rat dorsal hippocampus are able to induce long-term potentiation (LTP) at synapses ...[more]