Ontology highlight
ABSTRACT:
SUBMITTER: Hashimoto T
PROVIDER: S-EPMC4785961 | biostudies-literature | 2016 Apr
REPOSITORIES: biostudies-literature
Hashimoto Teruo T Fukui Kento K Takeuchi Hikaru H Yokota Susumu S Kikuchi Yoshie Y Tomita Hiroaki H Taki Yasuyuki Y Kawashima Ryuta R
Cerebral cortex (New York, N.Y. : 1991) 20160131 4
The Val66Met polymorphism of brain-derived neurotrophic factor (BDNF) is associated with psychiatric disorders and regional gray matter volume (rGMV) in adults. However, the relationship between BDNF and rGMV in children has not been clarified. In this 3-year cross-sectional/longitudinal (2 time points) study, we investigated the effects of BDNF genotypes on rGMV in 185 healthy Japanese children aged 5.7-18.4 using magnetic resonance imaging (MRI) and voxel-based morphometry (VBM) analyses. We f ...[more]