Ontology highlight
ABSTRACT:
SUBMITTER: Warner JF
PROVIDER: S-EPMC4790456 | biostudies-literature | 2016 Mar
REPOSITORIES: biostudies-literature
Warner Jacob F JF Miranda Esther L EL McClay David R DR
Developmental biology 20160209 2
Most bilaterians exhibit a left-right asymmetric distribution of their internal organs. The sea urchin larva is notable in this regard since most adult structures are generated from left sided embryonic structures. The gene regulatory network governing this larval asymmetry is still a work in progress but involves several conserved signaling pathways including Nodal, and BMP. Here we provide a comprehensive analysis of Hedgehog signaling and it's contribution to left-right asymmetry. We report t ...[more]