Ontology highlight
ABSTRACT:
SUBMITTER: Amata E
PROVIDER: S-EPMC4791575 | biostudies-literature | 2016 Mar
REPOSITORIES: biostudies-literature
ACS infectious diseases 20160117 3
A kinase-targeting cell-based high-throughput screen (HTS) against <i>Trypanosoma brucei</i> was recently reported, and this screening set included the Published Kinase Inhibitor Set (PKIS). From the PKIS was identified 53 compounds with pEC<sub>50</sub> ≥ 6. Utilizing the published data available for the PKIS, a statistical analysis of these active antiparasitic compounds was performed, allowing identification of a set of human kinases having inhibitors that show a high likelihood for blocking ...[more]