Ontology highlight
ABSTRACT:
SUBMITTER: Favrot L
PROVIDER: S-EPMC4795176 | biostudies-literature | 2016 Feb
REPOSITORIES: biostudies-literature
Biochemistry 20160209 7
The GCN5-related N-acetyltransferases family (GNAT) is an important family of proteins that includes more than 100000 members among eukaryotes and prokaryotes. Acetylation appears as a major regulatory post-translational modification and is as widespread as phosphorylation. N-Acetyltransferases transfer an acetyl group from acetyl-CoA to a large array of substrates, from small molecules such as aminoglycoside antibiotics to macromolecules. Acetylation of proteins can occur at two different posit ...[more]