Ontology highlight
ABSTRACT:
SUBMITTER: Perisin M
PROVIDER: S-EPMC4796925 | biostudies-literature | 2016 Apr
REPOSITORIES: biostudies-literature
Perisin Matthew M Vetter Madlen M Gilbert Jack A JA Bergelson Joy J
The ISME journal 20150911 4
The 16S rRNA gene (16S) is an accepted marker of bacterial taxonomic diversity, even though differences in copy number obscure the relationship between amplicon and organismal abundances. Ancestral state reconstruction methods can predict 16S copy numbers through comparisons with closely related reference genomes; however, the database of closed genomes is limited. Here, we extend the reference database of 16S copy numbers to de novo assembled draft genomes by developing 16Stimator, a method to ...[more]