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Cross-Neutralization between Human and African Bat Mumps Viruses.

ABSTRACT: Recently, a new paramyxovirus closely related to human mumps virus (MuV) was detected in bats. We generated recombinant MuVs carrying either or both of the fusion and hemagglutinin-neuraminidase bat virus glycoproteins. These viruses showed replication kinetics similar to human MuV in cultured cells and were neutralized efficiently by serum from healthy humans.

SUBMITTER: Katoh H

PROVIDER: S-EPMC4806932 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature

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Cross-Neutralization between Human and African Bat Mumps Viruses.

Katoh Hiroshi H Kubota Toru T Ihara Toshiaki T Maeda Ken K Takeda Makoto M Kidokoro Minoru M

Emerging infectious diseases 20160401 4

Recently, a new paramyxovirus closely related to human mumps virus (MuV) was detected in bats. We generated recombinant MuVs carrying either or both of the fusion and hemagglutinin-neuraminidase bat virus glycoproteins. These viruses showed replication kinetics similar to human MuV in cultured cells and were neutralized efficiently by serum from healthy humans. ...[more]

PMID: 26982800

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