Ontology highlight
ABSTRACT:
SUBMITTER: Beaty SM
PROVIDER: S-EPMC5854012 | biostudies-literature | 2017 Jan
REPOSITORIES: biostudies-literature
Beaty Shannon M SM Nachbagauer Raffael R Hirsh Ariana A Vigant Frederic F Duehr James J Azarm Kristopher D KD Stelfox Alice J AJ Bowden Thomas A TA Duprex W Paul WP Krammer Florian F Lee Benhur B
The Journal of infectious diseases 20170101 2
To evaluate the antigenic relationship between bat mumps virus (BMV) and the JL5 vaccine strain of mumps virus (MuVJL5), we rescued a chimeric virus bearing the F and HN glycoproteins of BMV in the background of a recombinant JL5 genome (rMuVJL5). Cross-reactivity and cross-neutralization between this chimeric recombinant MuV bearing the F and HN glycoproteins of BMV (rMuVJL5-F/HNBMV) virus and rMuVJL5 were demonstrated using hyperimmune mouse serum samples and a curated panel of human serum. Al ...[more]