Ontology highlight
ABSTRACT:
SUBMITTER: Yla-Pelto J
PROVIDER: S-EPMC4810247 | biostudies-literature | 2016 Feb
REPOSITORIES: biostudies-literature
Ylä-Pelto Jani J Tripathi Lav L Susi Petri P
Viruses 20160223 3
Research on human enteroviruses has resulted in the identification of more than 100 enterovirus types, which use more than 10 protein receptors and/or attachment factors required in cell binding and initiation of the replication cycle. Many of these "viral" receptors are overexpressed in cancer cells. Receptor binding and the ability to replicate in specific target cells define the tropism and pathogenesis of enterovirus types, because cellular infection often results in cytolytic response, i.e. ...[more]