Ontology highlight
ABSTRACT:
SUBMITTER: Anasir MI
PROVIDER: S-EPMC7811253 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Anasir Mohd Ishtiaq MI Zarif Faisal F Poh Chit Laa CL
Journal of biomedical science 20210115 1
Viruses from the genus Enterovirus (EV) of the Picornaviridae family are known to cause diseases such as hand foot and mouth disease (HFMD), respiratory diseases, encephalitis and myocarditis. The capsid of EV is an attractive target for the development of direct-acting small molecules that can interfere with viral entry. Some of the capsid binders have been evaluated in clinical trials but the majority have failed due to insufficient efficacy or unacceptable off-target effects. Furthermore, mos ...[more]