Ontology highlight
ABSTRACT:
SUBMITTER: Imamura H
PROVIDER: S-EPMC4811772 | biostudies-literature | 2016 Mar
REPOSITORIES: biostudies-literature
eLife 20160322
Leishmania donovani causes visceral leishmaniasis (VL), the second most deadly vector-borne parasitic disease. A recent epidemic in the Indian subcontinent (ISC) caused up to 80% of global VL and over 30,000 deaths per year. Resistance against antimonial drugs has probably been a contributing factor in the persistence of this epidemic. Here we use whole genome sequences from 204 clinical isolates to track the evolution and epidemiology of L. donovani from the ISC. We identify independent radiati ...[more]