Ontology highlight
ABSTRACT:
SUBMITTER: Fuentes AL
PROVIDER: S-EPMC4815265 | biostudies-literature | 2016 Mar
REPOSITORIES: biostudies-literature
Fuentes Ana Lucia AL Hennessy Kathleen K Pascual Jacob J Pepe Nicole N Wang In I Santiago Alexander A Chaggan Cynthia C Martinez Jessica J Rivera Evelyn E Cota Paola P Cunha Christina C Nogaj Luiza A LA Moffet David A DA
Journal of herbal medicine 20160301 1
The extracts of 27 vegetables, spices and herbs were screened for their functional ability to inhibit the aggregation of islet amyloid polypeptide (IAPP, amylin) into toxic amyloid aggregates. The aggregation of IAPP has been directly linked to the death of pancreatic β-islet cells in type 2 diabetes. Inhibiting the aggregation of IAPP is believed to have the potential to slow, if not prevent entirely, the progression of this disease. As vegetables, spices and herbs are known to possess many dif ...[more]