Ontology highlight
ABSTRACT:
SUBMITTER: Diamantis N
PROVIDER: S-EPMC4815767 | biostudies-literature | 2016 Feb
REPOSITORIES: biostudies-literature
Diamantis Nikolaos N Banerji Udai U
British journal of cancer 20160107 4
Antibody-drug conjugates (ADCs) are an emerging novel class of anticancer treatment agents that combines the selectivity of targeted treatment with the cytotoxic potency of chemotherapy drugs. New linker technology associated with novel highly potent cytotoxic payloads has permitted the development of more effective and safe ADCs. In recent years, two ADCs have been licensed, T-DM1 and brentuximab vedotin, and are already establishing their place in cancer treatment. A plethora of ADCs are being ...[more]