BitterX: a tool for understanding bitter taste in humans.
Ontology highlight
ABSTRACT:
SUBMITTER: Huang W
PROVIDER: S-EPMC4819188 | biostudies-literature | 2016 Apr
REPOSITORIES: biostudies-literature
Publications
BitterX: a tool for understanding bitter taste in humans.
Huang Wenkang W Shen Qiancheng Q Su Xubo X Ji Mingfei M Liu Xinyi X Chen Yingyi Y Lu Shaoyong S Zhuang Hanyi H Zhang Jian J
Scientific reports 20160404
BitterX is an open-access tool aimed at providing a platform for identifying human bitter taste receptors, TAS2Rs, for small molecules. It predicts TAS2Rs from the molecular structures of arbitrary chemicals by integrating two individual functionalities: bitterant verification and TAS2R recognition. Using BitterX, several novel bitterants and their receptors were predicted and experimentally validated in the study. Therefore, BitterX may be an effective method for deciphering bitter taste coding ...[more]
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