Ontology highlight
ABSTRACT:
SUBMITTER: Ishitsuka M
PROVIDER: S-EPMC4819195 | biostudies-literature | 2016 Apr
REPOSITORIES: biostudies-literature
Ishitsuka Masayuki M Akutsu Tatsuya T Nacher Jose C JC
Scientific reports 20160404
Recently, the number of essential gene entries has considerably increased. However, little is known about the relationships between essential genes and their functional roles in critical network control at both the structural (protein interaction network) and dynamic (transcriptional) levels, in part because the large size of the network prevents extensive computational analysis. Here, we present an algorithm that identifies the critical control set of nodes by reducing the computational time by ...[more]